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A Verdict on the Vaccination Boogeyman

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Have you ever wondered why, exactly, vaccines are erroneously associated with autism? I'll tell you: In 1998, Dr. Andrew Wakefield held a press conference to announce that his research had revealed a possible link between the MMR vaccine and autism. He published his findings in the respected independent medical journal The Lancet, and spent the next few years promoting his vaccine-autism "concerns" through media outlets like the TV news magazine 60 Minutes.

The result was panic, a vaccination rates nosedive, and the resurrection of vaccine-preventable diseases like measles.

In 2004, it was revealed that Wakefield had also been conducting a separate, simultaneous study funded by lawyers seeking compensation for clients who claimed their children suffered from vaccine damage. Ten of Wakefield's twelve original paper co-authors, horrified by Wakefield's conflict of interest as well as the public health crisis they'd help cause, issued an official retraction in The Lancet [PDF], stating, "We wish to make it clear that in [Wakefield's] paper no causal link was established between MMR vaccine and autism as the data were insufficient."

But the retraction wasn't nearly as newsworthy as the original claims, and besides, it came too late: Anti-vaccination fears had been established, and were burgeoning. They were harnessed by gullible torch-wielding celebrity Jenny McCarthy, who leads media crusades to demand the "truth" about the vaccines she claims caused her son's autism, even while she encourages the enraged and the credulous to dismiss any evidence that contradicts her "Mommy Instinct" on the matter. Organizations like Autism Speaks milk the "tragedy" of autism to raise millions of dollars, then divert a disproportionate amount of those precious funds towards vaccine/autism research instead of using them to support autism families and adult autistics in need.

Wakefield has always denied any wrongdoing, even as the fallout from the Lancet retraction spurred his relocation from the UK to the United States. He has even occasionally gone on the offensive, using the media arm of Thoughtful House, his US autism organization, to try to discredit Brian Deer, the journalist whose ongoing research first revealed the extent of Wakefield's questionable actions. Though I can't fault Wakefield for acting out, as Deer's efforts led to Wakefield being investigated by the UK's General Medical Council (GMC) for professional misconduct.

Finally, after more than two years of expert witness testimonials, hearings, and deliberation, the GMC has reached a verdict [PDF]: They determined that Wakefield "acted unethically" during his original study. They also found that he violated the non-patient-contact guidelines of his research contract, that he conducted risky procedures such as spinal taps without sufficient basis, that he manipulated his findings, and that in general he conducted his research "dishonestly and irresponsibly." (Note that the GMC specifically did not address whether or not Wakefield's conclusions were valid. They didn't have to. The Lancet had already made its retraction.)

Wakefield continues to have staunch supporters despite the GMC's verdict, which is unsurprising to thinking members of the autism community. Wakefield has long been a darling to contrarian organizations like Age of Autism and Generation Rescue, who never stop confidently proclaiming that a horse is a cow, and encourage supporters to bully anyone who hears the animal neighing. They hypocritically castigate mild-mannered vaccine proponent Paul Offit for making money off vaccine patents though that is his job, while conveniently ignoring one of the goals behind Wakefield's Lancet study: to impugn the MMR vaccine so he could patent (and one assumes, reap the financial rewards from) a replacement vaccine.

How has Wakefield himself responded to the GMC's verdict? He keeps mooing. He keeps denying any wrongdoing. Just keep reminding yourself that he's a unethical cow.

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My thanks to the following bloggers for providing links, and for sharing their great big skeptic brains:

Updates

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Shannon Des Roches Rosa
Squidalicious.com parenting first, autism second
CanISitWithYou.org real tales of schoolyard terror and triumph
My Child Has Autism and I Vaccinate you heard me

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The Monkey Keeper 5 pts

Great post!  No offense to any parents of children with autism, but I think some people just need something to blame.  I'm a parent of a child who survived a stroke, and some parents of young survivors also blame the MMR jab.  I have never believed it, and the recent studies confirm my beliefs all the more.  

http://danielsmonkeypaws.blogspot.com ~ Tales of an awesome kid who also happens to be a stroke survivor, and the mama who loves him.

Shannon Des Roches Rosa 5 pts

Thanks Alisa. Dr. Michael Fitzpatrick wrote a particularly thorough and damning summary on the Wakefield saga and its collateral damage ( http://www.spiked-online.com/index.php/site/articl... ) (including the Lancet's retraction of his paper ( http://www.care2.com/causes/health-policy/blog/vac... ), which happened after I wrote this post). Here are some highlights that expand upon both my and your points:

It is difficult to feel much sympathy for Dr Wakefield even as he faces such a public humiliation. His decision to attend the protest outside the GMC but not to enter the building to face in person the decision of the tribunal is typical of his evasion of accountability to his peers and of responsibility for his actions. For the past decade Dr Wakefield has avoided the medical and scientific world, producing articles for vanity-published journals and attending only conferences of parents. He even avoids scientifically informed journalists: his only interview on the GMC decision was given to a sympathetic features writer at the Daily Telegraph. Though Dr Wakefield has always enjoyed the support of sycophantic journalists and wealthy patrons (especially in the US), he cannot avoid the professional ignominy that results from the GMC proceedings.

Shannon Des Roches Rosa
Squidalicious.com ( http://www.squidalicious.com ) parenting first, autism second
CanISitWithYou.org ( http://www.canisitwithyou.org ) real tales of schoolyard terror and triumph

alissa599 5 pts

Seriously, I enjoyed this article so much that I want to print it out and send it to my non-believing anti-vaccination friends!!

I am raising my son with Autism and I have NEVER believed that his Autism was caused by his vaccines.  First of all he was vaccinated in Dec. of 2002.  The beginning of 2002 'they' stopped putting thimerasol in the MMR's all together.  His pediatrician (who administered the vaccines) raises a daughter with Autism himself, and firmly believes in vaccinations.  Further proof for me still is that I have three confirmed diagnosis of Autism on BOTH sides of my family.  I absolutely believe it's in the 'gene's'.  I could go on and on...

Thanks for saying what needs to be said.  Wakefield was in it for the money and fame.  And Jenny McCarthey needs to realize that Autism can NEVER be 'cured' (at least, not at this time)... and that the effects of Autism can only be POSSIBLY diminished through therapy and diet.  In my opinion all she is doing is trying to provide false hope for everyone and scare them away from necessary vaccines.

lis

KGav 5 pts

Thank you for this well-written, informative post!

http://gavmenagerie.blogspot.com

lizditz 5 pts

Liz Ditz I Speak of Dreams ( http://lizditz.typepad.com )  lizditz@gmail.com

Manda2177, I see that you feel very strongly about this.  I'd like to hear more about your feelings and reasoning.  But I find myself confused in a number of ways  by your comment.

Are you addressing Shannon, the author of the original article?  I have re-read her article carefully and cannot see where she is "terrorizing".

Are you addressing natalienorton?  Her son really did die of whooping cough (pertussis). That's not "terrorizing", it is a fact for her family.   He's not the only infant to die of pertussis.  As it turns out, pertussis is still with us, and is highly contagious. Before the vaccine was available, pertussis killed about 4,000 children and adults every year.  (source: immunizationinfo.org)

One of the reasons that pertussis is still endemic (circulating in the population) is that the immunity conferred by childhood vaccination wanes after five to ten years, just as immunity to lockjaw (tetanus) does.  So as a regular part of public health, people need to be revaccinated against tetanus, to protect themselves only, and against pertussis, to provide protection for infants who are too young to be vaccinated.  Happily, the adult booster combines both tetanus and pertussis.  (source: many.  the easiest to understand is  immunizationinfo.org)

PKIDS is a national organization for kids who with compromized immune systems.  In 2008, they launched an awareness and action campaign about pertussis, "Silence the Sounds of Pertussis".  One part of the campaign urged adults who might be in contact with infants to have  a booster shot, which confers immunity to tetanus and pertussis.

Whether you are addressing Shannon or Natalie, you write  "Your facts are off".  What facts are not....well, factual?  Or verifiable? Everything Shannon wrote is more than supported by the links she embedded in her post.  The facts of Natalie's son's death are easily verifiable.

Manda2177 wrote You DONT have the right to scare people into making a personal choice.

Everybody, including manda2177:  there's this idea out there that the decision to vaccinate oneself or one's children is a "personal decision".  It isn't, unless you live in a cave and never encounter another person.  The vaccination decision is a public health decision.  Here's why:

Most vaccine-preventable diseases are contagious before the sick person appears ill. Thus your decision not to vaccinate yourself or your children has implications for others, if you are just out in the community.
At least in the United States, we have lost the infrastructure for preventing contagion.  In other words, before universal vaccination for infectious disease, most pediatric practices had isolation waiting rooms for children. Those have disappeared.  In the 2008 San Diego measles outbreak, at least 2 infants were infected by sharing a pediatric  waiting room with child with measles.

lizditz 5 pts

Liz Ditz I Speak of Dreams ( http://lizditz.typepad.com )  lizditz@gmail.com

http://www.bloomberg.com/apps/news?pid=20601102&am...

The Lancet ( http://www.thelancet.com/ ) medical journal retracted a 1998 study that linked a routine childhood vaccine to autism and bowel disease after a U.K. investigation found flaws in the research.

An investigation by the U.K. General Medical Council, which registers and licenses doctors, concluded in a report last week that three researchers led by Andrew Wakefield ( http://search.bloomberg.com/search?q=Andrew+Wakefi... ) at the Royal Free Hospital in London carried out invasive, unnecessary tests, failed to act in the best interest of the children, and misused public funds. It also said Wakefield didn’t disclose a conflict of interest as he was involved in legal claims against the vaccine makers.

“It has become clear that several elements of the 1998 paper by Wakefield et al are incorrect, contrary to the findings of an earlier investigation,” the editors of the Lancet wrote in a statement ( http://download.thelancet.com/flatcontentassets/pd... ) today.

Shannon Des Roches Rosa 5 pts

Manda2177,

I have faith that BlogHer's intelligent and fair-minded readers will decide for themselves after reading through the evidence I have cited. I also believe that they do not need to be protected from strong opinions with which they may or may not disagree. I advise you to give them the same credit.

Shannon Des Roches Rosa
Squidalicious.com ( http://www.squidalicious.com ) parenting first, autism second
CanISitWithYou.org ( http://www.canisitwithyou.org ) real tales of schoolyard terror and triumph

aspergers2mom 5 pts

Manda you are the one who sounds awfully angry.  Vaccines have saved millions of lives and has rid this planet of the pestilence of small pox. So anyone who says that vaccines are not proven successful is either misguided, ill informed or not willing to deal with the reality that there is no outside catalyst to autism other than a gene that you pass on to your children. 

 Just look at the recent measles outbreaks among college students. Because the vaccine wears off and most ppl do not revaccinate there is a risk of infection. Measles can cause, deafness, blindlness,  birth defects or death. You don't have all the facts and you don't have the right to scare people.

It is not a personal choice when that choice may lead to someone elses' death. Just like you don't have the right to drive drunk because it endangers someone else's life you do not have the right to expose others to harmful deadly and unnecessary diseases. Shame on you for your self-centeredness.

Elise http://asd2mom.spaces.live.com

Hey Jen 5 pts

your story, after reading about it through DPS. I saddened me greatly to read about his illness and subsequent death. Your faith in God amazed and touched me. 

manda2177 5 pts

The fact is, you sound like you are trying to TERRORIZE moms into believing what you say.  Your facts are off, your judgement critical, your theory misguided.  How dare you try and scare moms into vaccinating because YOU believe its the right thing to do?  Whether you want to admit it or not, there is a chance you are wrong.  Are you willing to take that chance with everyone who reads this?  You DONT have all the facts.  You DONT know everyting about vaccines.  You DONT have the right to scare people into making a personal choice. 

mrsL 5 pts

I think you're being rather simplistic Mandy - it is human nature to assign blame when tragedy happens.  Lord knows I've done that enough with my own personal tragedies. And with that I'm bowing out of this discussion.

Elena,

"If you bungle raising your children, nothing else much matters." Jackie Kennedy

greenjello1 5 pts

Yes, I did.  Wow, isn't it amazing how many people are under or not immunized?

It is always  hard to keep up on our immunizations, but thanks to articles like this or un-fortunate situations like Baby Gavin it raises our awareness of immunizations. 

I know that I didn't realize all the booster shots I should get and thanks to Baby Gavin I was able to go get those to keep myself up to date.  For my own self and for those sweet little babies who are under immunized.

mrsL 5 pts

Greenjello I think you just indicted over 75% of the adult population - those who didn't know that they should get booster shots, and those whose immunity did not last the full 10 years between boosters.

Elena,

"If you bungle raising your children, nothing else much matters." Jackie Kennedy

mrsL 5 pts

The pertussis vaccine doesn't give lifelong immunity.  It is very possible to have been exposed to pertussis to someone who was previously vaccinated and simply became re-infected with it later in life.

Elena,

"If you bungle raising your children, nothing else much matters." Jackie Kennedy

natalienorton 5 pts

Oops!  By December 2 I meant December 29. . . so he was admitted on the 29th, died the 7th. 

natalienorton 5 pts

It is terrifying to me how many parents are opting out of vaccinations these days. 

On December 2th, my 8 week old son, Gavin was admitted to the hospital.  Doctors thought he had a severe case of RSV.  Within a few days, he was transferred to the PICU and given the positive diagnosis of pertussis. . . he died January 7th. 

He died because someone else chose not to vaccinate.  He was too young to have received the first of the series of shots that protect children from the disease. 

If you're interested, you can read more about my son's illness and subsequent death at www.natalienortonphoto.com.  ( http://www.natalienortonphoto.com.  ) Search label, baby gavin.  Scroll down to read the first posts describing his illness.  I promise you, were you to see your child suffer the way mine did, you'd be the first in line for vaccinations of any sort. 

greenjello1 5 pts

Natalie,

I have been following your story from the beginning (from Kara A.).  My sincere heartfelt compassion goes out to you and your baby Gavin.

Whatever the source of Gavin's pertussis, the fact remains that those who should be vaccinated (babies, or adults who need a booster shot) hold the responsibility of care for those little ones who can not be vaccinated .

The funny thing to me is the reason why these diseases have become rare is because of vaccination, so those who choose to not vaccinate their children and pay no price for it have those who do vaccinate themselves and their children to thank for it.

And, I suspect that you would love a chance to bungle raising Baby Gavin ;)

Shannon Des Roches Rosa 5 pts

Done! Though Liz Ditz's problems are obviously fixed (see below).

Shannon Des Roches Rosa
Squidalicious.com ( http://www.squidalicious.com ) parenting first, autism second
CanISitWithYou.org ( http://www.canisitwithyou.org ) real tales of schoolyard terror and triumph

lizditz 5 pts

Liz Ditz I Speak of Dreams ( http://lizditz.typepad.com ) lizditz@gmail.com

Let's see if this comment goes through.  I couldn't figure out what was wrong -- kept getting trapped in the spam filter even after I took out all the URLs.  Thanks, Shannon for helping.

Elena, thank you for your understanding.

I was paying really close attention to the national U.S. flu stats before the vaccine became available because my daughter-in-law is pregnant and the other grandchildren were also high-risk.  I got really nervous around Thanksgiving because several schools in our area closed early, or for an extended period, because of high rates of flu-caused absences.

The novel H1N1 didn't strike uniformly in the US.  Seems like there were pockets of severe disease (high rate disease, with high rates of hospitalizations and deaths). So if you (for example) weren't in one of the pockets, it might indeed have appeared that H1N1 was overblown.

Thankfully, my family too has been unusually healthy so far this winter.

Wakefield's famous press conference was in 1998 -- the "autistic entercolitis" show was on the road.  The "do vaccines cause autism" debate changed in 1999, with the suspicion that thimerosal in vaccines had something to do with autism.  Safe Minds was founded in 2000 and Generation Rescue in the spring of 2005. At the time Safe Minds was founded,  "vaccines cause autism?" was a reasonable question, as the research had not yet been completed. 

But by 2007 (at the latest), the studies had been done. Wakefield's research had been thoroughly discredited on several grounds. Further, no link between thimerosal and autism could be found.  Safe Minds, Generation Rescue,and Age of Autism moved the goal posts.  Now it was "toxins" and later, "too many too soon."

I think for those of us who are science-based advocates for people with autism, the years of frustration with Wakefield and his allies is just assumed.  Someone who isn't familiar with the backstory may not understand what the GMC ruling means in terms of those years of frustration.

Denise 9 pts moderator

Shannon, if you hear of someone having problems leaving a comment, can you pass along my email address and ask them to contact me with specific information about what the problem is? Error message? Something else entirely?

~Denise BlogHer Community Manager
Flamingo House Happenings ( http://www.flamingohouse.net/ )

mrsL 5 pts

Please tell Ms. Ditz thank you for her reply.  i don't know enough about Dr. Wakefield to make a judgement about him one way or another however I do understand how know of other scientiests have been blackballed, lost jobs, tenure, etc. for not towing the popular line on other subjects i.e. intelligent design and climate change - so I'll take it all with a grain of salt.

There is enough anecdotal evidence to make me cautious and suspicious, but I have been that way about corporate American medicine  ever since I was railroaded into an unnecessary Cesarean section the first time. US doctors frequently use practices, procedures and medications in ways that are not in the best interest of the patient and I have no doubt that vaccines could be the same way. It's not like they don't have support from big Pharma.

Sorry about you friend's experience and hope her child is healthy soon. None of my family (including 6 kids, one of whom is an adult working as an EMT) got the vaccine and none of us got sick.  Not even a sore throat this year. 

Elena,

"If you bungle raising your children, nothing else much matters." Jackie Kennedy

Shannon Des Roches Rosa 5 pts

Apparently some users are having problems commenting &/or posting blog entries. Possibly an IE issue?

Shannon Des Roches Rosa
Squidalicious.com ( http://www.squidalicious.com ) parenting first, autism second
CanISitWithYou.org ( http://www.canisitwithyou.org ) real tales of schoolyard terror and triumph

Shannon Des Roches Rosa 5 pts

Moms believe her because she is a professional performer. I don't know of any scientists or doctors who could match her stage presence or name recognition, do you? It's like asking why reality TV is more popular than NPR.

Shannon Des Roches Rosa
Squidalicious.com ( http://www.squidalicious.com ) parenting first, autism second
CanISitWithYou.org ( http://www.canisitwithyou.org ) real tales of schoolyard terror and triumph

Shannon Des Roches Rosa 5 pts

Barbara Loe Fisher (the author of Elena's link) has turned her valid cause - rare but legitimate adverse vaccine reactions - into an antivaccination campaign so monolithic that her supporters now protest any pro-vaccine stance ( http://www.ageofautism.com/2010/01/naked-intimidat... ), including Bill Gates's intention to "commit $10 billion over the next 10 years ( http://www.gatesfoundation.org/press-releases/Page... ) to help research, develop and deliver vaccines for the world’s poorest countries."

Ms. Fisher's intentions are good, but she, like Wakefield, is a threat to public health.

"The old fashioned way" of getting vaccine-preventable diseases kills people. The oft-cited vaccines = seatbelts analogy applies here - most people who don't wear seatbelts don't die, but is that reason enough not to wear them?

Regardless, I appreciate that you continue to follow BlogHer's policy of civil disagreement.

Shannon Des Roches Rosa
Squidalicious.com ( http://www.squidalicious.com ) parenting first, autism second
CanISitWithYou.org ( http://www.canisitwithyou.org ) real tales of schoolyard terror and triumph

Shannon Des Roches Rosa 5 pts

Liz Ditz asked me to post this for her:

BlogHer hates me and won't let me post. Even if I take out the links, the comment 'triggers the spam filter'

Here's what I wanted to say:

Elena, there's only one correct answer to some questions, such as "Is the Earth Flat?" or "Is the Earth the Center of the Universe?"

And there's only one correct side to the Wakefield story. He violated his oath as a doctor on numerous occasions. He lied about his motives and his source of funding. He endangered children.

As to the novel H1N1 "flopping". That's the pinch in public health. When you do it right, nothing happens. Still, in the U.S., 10,837 people died. And my blog-friend, Attila the Mom? Her son was hospitalized with H1N1, and was not expected to survive. After a 45 day hospitalization, he came home. But now at day 92, her son's still on oxygen.

And about the "more vaccinations". Yes, we are inoculating against more diseases, but the antigen load is smaller.

from http://www.chop.edu/service/vaccine-education-cent...

Thirty years ago, children received seven vaccines, which protected against measles, mumps, rubella, diphtheria, tetanus, pertussis and polio. The total number of bacterial and viral proteins contained in these seven vaccines was a little more than 3,000.

Today, children receive 14 different vaccines, but the total number of immunological components in these vaccines is only about 150. This dramatic reduction is the result of scientific advances that have allowed for purer, safer vaccines.

Are vaccines perfect? Not by a long shot. But they are safer than the diseases they prevent.

Here is what I object to about Wakefield (and Thoughtful House, Age of Autism, Generation Rescue, and even Autism Speaks). Their focus on "a cure for autism" sucks up the time and money that should be going to:

Increasing support for families who have one or more members with autism
Increasing educational opportunities for people with autism -- safe, welcoming, and effective educational opportunities
Increasing opportunities for dignified, meaningful employment for people with autism
Increasing safe and dignified living arrangements for those with autism who cannot manage independent living.
-Liz Ditz ( http://lizditz.typepad.com/ )

daisymayfattypants 5 pts

Some stories just have one side, the side that has the facts on it. This is one of those stories.

Cheers!

Emily

mrsL 5 pts

so here's an article about the other side.

http://vaccineawakening.blogspot.com/2010/01/vacci... ( http://vaccineawakening.blogspot.com/2010/01/vacci... )

Personally, I don't trust anything.  H1 N1 was supposed to be such a big deal - and now they can't give the vaccine away and the mass school closings and everything they were predicting never happened in my state. 

But what really bugs me is that we are giving more vaccinations for everything to little kids and we don't really know how that is going to affect them 20, 30, 40 or more years down the line - and that scares the hell out of me too.  and I say that as someone who had measles, mumps, rubella and chickenpox the old fashioned way!

Elena,

"If you bungle raising your children, nothing else much matters." Jackie Kennedy

healthyperhaps 5 pts

Thanks for explaining the cause of this vaccine ignorance! Mommies like Jenny McCarthy are so dangerous.... Why Moms believe her over scientists, I will never understand!

Sierra Black 5 pts

So glad that odious man finally got smacked down by the establishment. He's hurt a lot of people, including his most ardent supporters.

daisymayfattypants 5 pts

The next step for the GMC is consideration of whether or not to strike him from the registry. He is not licensed to practice medicine in the US, although to hear some of the people who go to Thoughtful House tell it, he practically heals their children directly through a laying on of hands.

Cheers! Emily

texasebeth 6 pts

While I know some parents with children who are diagnosed with any horrible disease, whether it is autism, cystic fibrosis, etc., are desparate to find someone or something to blame, there is not just 1 answer to who or what is at fault. Some times it is genetics pure and simple, sometimes it is a myriad of things, sometimes there is nothing nor noone to blame - it just happened.

I spent part of my growing up years in southern Sudan & saw people die from diseases that could have been prevented by vaccines.  I had an older relative who had Polio. My son is vaccinated. I do the research, I educate myself from a WIDE variety of sources, not just the Internet or websites, books, doctors who believe as I do. I research both sides of the issue and make the best informed decision I can.

I just wish the media would be as vocal about the errors & retractions as they were about the original study. Unfortunately, that will never happen so the misinformation campaign will continue, ultimately hurting the ones who need the help the most - the families and kids.

Elizabeth

http://texasebeth.blogspot.com

aspergers2mom 5 pts

Elise http://asd2mom.spaces.live.com

I had always know that vaccines did not cause my children's autism. It is about time that those who perpetrated this fraud be held up to the ridicule they deserve. It is truamatizing to think of all the money wasted and research time misspent investigating and then refuting the "vaccine as evildoer"  mantra. How much farther ahead would we be in truely finding an actual medical answer to the quandry that is autism, if Wakefield along with the irresponsible MSM and hollywood know-it-alls did not perpetrate this falaceous credo.

BTW don't forget the biomed doctors who make a fortune feeding the fears and praying on desperate parents. An entire industry has evolved based upon Wakefield's malfeasance. Talk about those with a money-ax to grind.

daisymayfattypants 5 pts

done a lovely, precise job of putting it all together coherently. Well done. And funny withal, to boot.

Cheers! Emily

stephaniedelger 5 pts

This is exactly what people need to hear.  I've certainly researched the vaccines my children get; I've weighed the pros and cons (didn't take long - polio=bad, not getting polio=probably the way to go) and the only one I've opted out of is the H1N1. 

I find it very irresponsible to refuse the majority of well child vaccinations based on a claim most people have known for years is suspect (at best).

Thanks for a great post!